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The Naglu −/− cells (the line with metabolic disease), compared to cells of the WT line, have a documented lower antioxidant potential and a lower activity of sulfurtransferases enzymes [43]
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The QSAR models show which structural components of BACE1 inhibitors include hydrophobic aromatic rings and hydrogen bond acceptors that developers can use to design new BACE1 inhibitor compounds (Kumar et al., 2020)
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