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Although sorafenib influences metastasis and proliferation through multiple targets, such as VEGFR, Raf, and PDGFR, some HCC tumors do not overexpress these targets [125]
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The incidence of graft loss in the heterozygous genotype (AG) of GSTA1 A-513G was 40% compared to 8% in the wild type genotype (AA) and the difference was statistically significant ( p = 0.006)
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