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Discovery of Nrf2 Nrf2 was first identified by researchers in the laboratory of Yuet Wai Kan using a λgt11 cDNA expression library to screen for proteins that bind to an extended activator protein 1 (AP-1) sequence (i.e., 5′-TGA C / G TCA-3′) [63]
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The role of meningeal lymphatics in communication between the brain and the peripheral immune system is discussed within the context of CNS-related immune responses
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