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therefore, it is entirely plausible to hypothesize that, especially in the presence of high dosages, these drugs can bind in a non-specific manner to other molecules different from their target, which could be the reason for the secondary effects of cytotoxicity
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Differences in cell viability and rescue assays between the control and treatment groups were analyzed using a Williams' test, and the combination effects were evaluated using a two-way analysis of variance followed by a Tukey's test
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