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Chemical information Name: Dihexa CAS Number: 1401708-83-5 Also known as: PNB-0408, ATH-1001, Hexanoyl-Tyr-Ile-Ahx-NH2, N-hexanoic-Tyr-Ile-(6)-aminohexanoic amide Sequence: Hexanoyl-Tyr-Ile-Ahx-NH2 Type: Synthetic oligopeptide (Angiotensin IV analog) Molecular formula: C27H44N4O5 Molecular weight: ≈504.67 g/mol Studied applications HGF/c-Met receptor signalling research Dendritic spinogenesis and synaptic connectivity studies in neuronal models Comparative research against native Angiotensin IV PI3K/AKT-associated pathway research Solubility & handling note Published vendor datasheets report that Dihexa is soluble in DMSO (brief ultrasonic treatment assists dissolution) and only slightly soluble in aqueous media, so DMSO or an equivalent organic solvent is typically selected for stock preparation
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Strength:50 mg (60 Tablets)
However, studies conducted concurrently showed unexpected superiority of once-weekly forms of GLP-1 drug candidates to daily forms, and raised questions as to whether the addition of GIP was necessary for a useful incretin agonist
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