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Mechanistic evaluation and transcriptional signature of a glutathione S-transferase omega 1 inhibitor | Nature Communications
Hence, exogenous lactate stabilizes HIF-1α by acting as a substrate for pyruvate production, and a high lactate concentration in the TME ensures the transcriptional activation of tumor-promoting genes in all tumor cells regardless of oxygen supply
Antioxidant support
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ESPEN-ESPGHAN-ECFS guidelines on nutrition care for infants, children, and adults with cystic fibrosis
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