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The categorization is complicated not just by the mixed properties of tianeptine itself, but by the likelihood that antidepressants improve cognition in depressed people [38] and the possibility that some mu opioids might function as antidepressants [39–41]
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The peptide backbone is synthesized with L-amino acids and then inverted into D-amino acids to form the D-retro-inverso (DRI) version, which enhances enzymatic stability and efficacy in research settings
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