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Nutritional deficiencies Crohn’s disease often leads to deficiencies that need monitoring and, sometimes, supplementation: Iron (from blood loss and poor absorption) Vitamin B12 (especially if the end of the small intestine is affected or has been removed) Vitamin D Calcium Folate Zinc Foods often discussed Some people find that certain foods worsen their symptoms — commonly high-fibre foods during flares, very spicy foods, large amounts of dairy if lactose intolerant, alcohol, and ultra-processed foods